Lv2
140 积分 2024-02-28 加入
Journey of Methionine Adenosyltransferase 2A Inhibitors: From Bench to Advanced Clinical Trials
5天前
已完结
The evolving landscape of RAS-targeted therapies
10天前
已完结
Discovery and Optimization of a Potent, Efficacious, and Brain-Penetrant Inhibitor of KRAS G12C
10天前
已完结
Approved Steroidal Drugs (2000–2025): A Medicinal Chemistry Perspective
1个月前
已完结
Orally Bioavailable Small-Molecule CD73 Inhibitor (OP-5244) Reverses Immunosuppression through Blockade of Adenosine Production
4个月前
已完结
Discovery of Novel Non-Nucleoside Inhibitors Interacting with Dizinc Ions of CD73
4个月前
已完结
Abstract 2074: ORIC-533, a small molecule CD73 inhibitor with best-in-class properties, reversesimmunosuppression and has potential as an immunomodulatory therapy in patients with multiple myeloma
4个月前
已完结
Discovery of ORIC-533, an Orally Bioavailable CD73 Inhibitor That Maintains Activity in High AMP Environments to Reverse Tumor Immunosuppression
4个月前
已完结
Development of Novel PTPN2/1 Inhibitors for the Treatment of Melanoma
4个月前
已完结
Design and Synthesis of Senescence-Targeted Prodrugs with Senomorphic and Senolytic Properties To Mitigate Chemotherapy-Induced Kidney Injury
4个月前
已完结