李RP
Lv11
48 积分
2025-03-19 加入
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[11] Vijayasarathy, M.; Basheer, S. M.; Balaram, P., Cone Snail Glutaminyl Cyclase Sequences from Transcriptomic Analysis and Mass Spectrometric Characterization of Two Pyroglutamyl Conotoxins[J]. J. Proteome Res., 2018, 17(8): 2695-2703
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[9] SCHILLINGS,HOFFMANNTROSCHEFetal.Heterologousexpressionandcharacterization of human glutaminyl cyclase: evidence for a disulfide bond with importancefor catalytic activity [J]. Biochemistry, 2002, 41(35): 10849-57
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[6] Nussbaum J M, Schilling S, Cynis H, et al. Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-beta[J]. Nature, 2012,485(7400):651-655
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[4] SAIDO T C, YAMLAO-HARIGAYA W, IWATSUBO T, et al. Amino- and carboxyl-terminalheterogeneity ofbeta-amyloid peptides deposited in human brain [J]. Neuroscience letters, 1996.215(3): 173-63
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Advances of computer-aided drug design (CADD) in the development of anti-Azheimer's-disease drugs
2个月前
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Pharmacophore-driven identification of human glutaminyl cyclase inhibitors from foods, plants and herbs unveils the bioactive property and potential of Azaleatin in the treatment of Alzheimer's disease
3个月前
已完结
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Deciphering Glutaminyl Cyclase Catalytic Pathways Enables Recognition of Anchor Pharmacophores for Inhibitor Discovery
3个月前
已完结
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猪流行性腹泻病毒S蛋白外分泌信号肽筛选及稳定表达细胞系的构建
4个月前
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Identification of benzimidazole-6-carboxamide based inhibitors of secretory glutaminyl cyclase for the treatment of Alzheimer's disease
4个月前
已完结
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Targeting QPCTL: An Emerging Therapeutic Opportunity
4个月前
已完结