Lv4
788 积分 2023-07-09 加入
Highly Selective Inhibition of Tyrosine Kinase 2 (TYK2) for the Treatment of Autoimmune Diseases: Discovery of the Allosteric Inhibitor BMS-986165
8天前
已完结
ITK degradation to block T cell receptor signaling and overcome therapeutic resistance in T cell lymphomas
8天前
已完结
Itk tyrosine kinase substrate docking is mediated by a nonclassical SH2 domain surface of PLCgamma1
8天前
已完结
T-cell signaling regulated by the Tec family kinase, Itk
8天前
已完结
ITK inhibitors in inflammation and immune-mediated disorders
9天前
已完结
Crystal structures of interleukin-2 tyrosine kinase and their implications for the design of selective inhibitors
9天前
已完结
Balancing fate with Itk
9天前
已完结
T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3
10天前
已完结
Multidomain Control Over TEC Kinase Activation State Tunes the T Cell Response
14天前
已完结
Scaffold Protein SLP-76 Primes PLCγ1 for Activation by ITK-Mediated Phosphorylation
15天前
已完结