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4901 积分 2021-04-28 加入
YN1548: A Novel Small-molecule Agonist of Human Glucagon-like Peptide-1 Receptor for the Treatment of Type 2 Diabetes Mellitus and Obesity
2小时前
已完结
Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators
1天前
已完结
Calculation-assisted regioselective functionalization of the imidazo[1,2-a]pyrazine scaffold via zinc and magnesium organometallic intermediates
2个月前
已完结
The European Federation for Medicinal Chemistry and Chemical Biology (EFMC) Best Practice Initiative: Hit to Lead
2个月前
已完结
18O-Enabled High-Throughput Acyl Glucuronide Stability Assay
2个月前
已完结
An update for AlphaFold3 versus experimental structures: assessing the precision of small molecule binding in GPCRs
2个月前
已完结
Amycretin, a novel, unimolecular GLP-1 and amylin receptor agonist administered subcutaneously: results from a phase 1b/2a randomised controlled study
3个月前
已完结
PROTAC Linkerology Leads to an Optimized Bivalent Chemical Degrader of Polycomb Repressive Complex 2 (PRC2) Components
3个月前
已完结
Amylin: emergent therapeutic opportunities in overweight, obesity and diabetes mellitus
3个月前
已完结
The changing landscape of medicinal chemistry optimization
3个月前
已完结
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