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Discovery and structure-activity relationship of cannabidiol aminoquinones as anti-Alzheimer's agents via dual modulation of Nrf2/HO-1 and TLR4/NF-κB pathways
12小时前
待确认
Novel serine-derived Phosphinic peptides as potent MMP-13 inhibitors
13小时前
已完结
SDP-LIV1, a Novel and Optimized LIV-1 Antibody–Drug Conjugate Demonstrating Superior Antitumor Efficacy and a Favorable Safety Profile for the Treatment of Solid Tumors
15小时前
已完结
A first-in-class small-molecule inhibitor targeting AVIL exhibits safety and antitumor efficacy in preclinical models of glioblastoma
1天前
已完结
Development of the first-in-class RNF4 PROTAC degrader as potential therapeutics for hepatocellular carcinoma
1天前
已完结
Rational design of dual PB2/JAK2 inhibitors achieving balanced antiviral and host-directed immunomodulatory effects
1天前
已完结
Discovery and optimization of Menin-MLL inhibitors targeting acute myeloid leukemia
1天前
已完结
Discovery of novel ENPP1 inhibitors with benzotriazole core for cancer immunotherapy
1天前
已完结
Synthesis, Biological evaluation and Mechanism study of 2-benzoyl-quinazolinone derivative as ferroptosis inhibitor for the treatment of Parkinson’s disease
1天前
已完结
ETC-501 is a Brain Penetrant MNK Kinase Inhibitor that Potentiates TMZ-Induced Senescence and Sensitizes Glioblastoma Cells to Senolytic Therapy
2天前
已完结
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