Lv41
406 积分 2025-12-22 加入
Enhancer reprogramming underlies therapeutic utility of a SMARCA2 degrader in SMARCA4 mutant cancer
1小时前
待确认
Glutathione-dependent degradation of SMARCA2/4 for targeted lung cancer therapy with improved selectivity
2小时前
已完结
Targeting the mSWI/SNF complex in POU2F-POU2AF transcription factor-driven malignancies
2小时前
已完结
PRT3789 Is a First-in-Human SMARCA2-Selective Degrader That Induces Synthetic Lethality in SMARCA4 -Mutated Cancers
2小时前
已完结
Small Molecules Co-targeting CKIα and the Transcriptional Kinases CDK7/9 Control AML in Preclinical Models
1个月前
已完结
Targeted protein degradation: expanding the toolbox
1个月前
已完结
Lessons learned in linking PROTACs from discovery to the clinic
2个月前
已完结
TRPM channels in health and disease
3个月前
已完结
Combinatorial use of VHL and KEAP1 PROTACs reveals unexpected synergy and hook effect relief
3个月前
已完结
High-throughput diversification of protein-ligand surfaces to discover chemical inducers of proximity
3个月前
已完结
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