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360 积分 2025-12-22 加入
Unexplored therapeutic opportunities in the human genome
1个月前
已完结
How to Illuminate the Druggable Genome Using Pharos
1个月前
已完结
A comprehensive map of molecular drug targets
1个月前
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The evolving landscape of drug targets
1个月前
已完结
Targeting CDKs in the RNAPII transcription cycle
2个月前
已完结
Enhancer reprogramming underlies therapeutic utility of a SMARCA2 degrader in SMARCA4 mutant cancer
3个月前
已完结
Glutathione-dependent degradation of SMARCA2/4 for targeted lung cancer therapy with improved selectivity
3个月前
已完结
Targeting the mSWI/SNF complex in POU2F-POU2AF transcription factor-driven malignancies
3个月前
已完结
PRT3789 Is a First-in-Human SMARCA2-Selective Degrader That Induces Synthetic Lethality in SMARCA4 -Mutated Cancers
3个月前
已完结
Small Molecules Co-targeting CKIα and the Transcriptional Kinases CDK7/9 Control AML in Preclinical Models
5个月前
已完结
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