Lv4
620 积分 2025-11-01 加入
Metabolic activation of drugs by cytochrome P450 enzymes: Biochemical insights into mechanism-based inactivation by fibroblast growth factor receptor inhibitors and chemical approaches to attenuate reactive metabolite formation
4天前
已完结
Targeting the Tyrosine Kinase 2 (TYK2) Pseudokinase Domain: Discovery of the Selective TYK2 Inhibitor ABBV-712
4天前
已完结
An Introduction to Medicinal Chemistry
11天前
已完结
Cross-Electrophile Coupling: Principles, Methods, and Applications in Synthesis
1个月前
已完结
Construction of C-S and C-Se Bonds via Deaminative Coupling of Primary Amines
1个月前
已完结
The Buchwald–Hartwig Amination After 25 Years
2个月前
已完结
Discovery of (2R)-N-[3-[2-[(3-Methoxy-1-methyl-pyrazol-4-yl)amino]pyrimidin-4-yl]-1H-indol-7-yl]-2-(4-methylpiperazin-1-yl)propenamide (AZD4205) as a Potent and Selective Janus Kinase 1 Inhibitor
2个月前
已完结
Practical and Scalable Method for Manufacturing AZD4604, A Potent and Selective JAK1 Inhibitor
2个月前
已完结
Direct Construction of Chiral Ether via Highly Efficient Heck Reaction and N-Directed Asymmetric Hydrogenation for Large-Scale Synthesis of MALT1 Inhibitor RGT-068A
2个月前
已完结
Mechanistic Investigation of a Domino N–H and C–H Borylation in the Manufacture of AMG 193
2个月前
已完结
皖公网安备34019202002308
