Lv5
1582 积分 2022-02-27 加入
Targeting Cyclic GMP–AMP Synthase: Novel Therapeutic Inhibitors for Autoimmune Diseases
2小时前
待确认
Discovery and characterization of a novel cGAS covalent inhibitor for the treatment of inflammatory bowel disease
4小时前
待确认
Selective cGAS inhibition is cardioprotective after myocardial infarction
1天前
待确认
Rearrangement of Heterocycles via-2-oxoketenes: Synthesis and Rearrangement Reactions of Cross-Conjugated Mesomeric Pyridazino[2,3-a]pyrimidine
6天前
已关闭
Abstract CT117: Phase 1 study of HRS-6209, a highly selective CDK4 inhibitor, in patients with advanced solid tumors
9天前
已完结
Structure-Based Design of Potent TLR7/8/9 Triple Antagonists: Overcoming High Tissue Distribution and Reactive Metabolite Liabilities
14天前
已完结
Discovery of Bis-imidazolecarboxamide Derivatives as Novel, Potent, and Selective TNIK Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis
17天前
已完结
Structure-Based Design of a Novel Covalent 4-(1-Methylindol-3-yl)pyrimidin-2-amine Series Targeting FGFR2 Resistance Mutations
22天前
已完结
Identification and Mitigation of Reactive Metabolites of 2-Aminoimidazole-Containing Microsomal Prostaglandin E Synthase-1 Inhibitors Terminated Due to Clinical Drug-Induced Liver Injury
22天前
已完结
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