Lv1
30 积分 2022-08-06 加入
TRMT6-mediated tRNA m1A modification acts as a translational checkpoint of histone synthesis and facilitates colorectal cancer progression
12天前
已完结
Discovery of the First Potent PI3K/mTOR Dual-Targeting PROTAC Degrader for Efficient Modulation of the PI3K/AKT/mTOR Pathway
13天前
已完结
Targeting WIP1 reprograms immunosuppressive tumor microenvironment to potentiate immunotherapy response in colorectal cancer
14天前
已完结
Phosphodiesterase 4B is an effective therapeutic target in colorectal cancer
15天前
已完结
The selective degradation of PDE4B shortform, using a PROTAC, leads to inhibition of several hallmarks of cancer in HCT116 cells
15天前
已完结
Induced proximity pushes beyond protein degraders, as first RIPTAC moves into the clinic
21天前
已完结
Bringing atoms to bedside with targeted alpha therapy
1个月前
已完结
P3.13.05 First-In-Human Study of 225Ac-ABD147 for SCLC and LCNEC Post-Chemotherapy: Pharmacokinetics, Biodistribution and Safety Insights
1个月前
已关闭
Natural products as payloads for antibody-drug conjugates: Cyclopamine linked to cetuximab for hedgehog pathway inhibition
1个月前
已完结
Sacituzumab tirumotecan in advanced non-small-cell lung cancer with or without EGFR mutations: phase 1/2 and phase 2 trials
1个月前
已完结
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