Lv1
96 积分 2022-11-06 加入
Structure-based optimization of TEAD inhibitors: Exploring a novel subpocket near Glu347 for the treatment of NF2-mutant cancer
1个月前
已完结
Development of Novel Indole-Based Covalent Inhibitors of TEAD as Potential Antiliver Cancer Agents
1个月前
已完结
Small Molecule Inhibitors of TEAD Auto-palmitoylation Selectively Inhibit Proliferation and Tumor Growth of NF2 -deficient Mesothelioma
1个月前
已完结
Mining the CRBN Target Space Redefines Rules for Molecular Glue-induced Neosubstrate Recognition
1个月前
已完结
YAP/TEAD inhibitor VT3989 in solid tumors: a phase 1/2 trial
1个月前
已完结
NINJ1 monoclonal antibody alleviates neuroinflammation and promotes functional recovery after spinal cord injury by suppressing pyroptosis-mediated DAMPs release
2个月前
已完结
Discovery of Clinical Candidate IAG933, a Potent YAP-TEAD PPI Disrupter
2个月前
已完结
Development of a fluorescence-based assay for screening of urate transporter 1 inhibitors (II): Optimization of fluorescent substrates and structure-activity relationships analysis
2个月前
已完结
Discovery of a Potent and Orally Bioavailable Xanthine Oxidase/Urate Transporter 1 Dual Inhibitor as a Potential Treatment for Hyperuricemia and Gout
2个月前
已完结
Discovery of a Potent and Orally Bioavailable Xanthine Oxidase/Urate Transporter 1 Dual Inhibitor as a Potential Treatment for Hyperuricemia and Gout
2个月前
已完结
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