Lv6
1790 积分 2022-10-10 加入
Expanding Conjugate Space of RNAi Therapeutics: Ligand at the 3′ End of the Antisense Strand Achieves Uncompromised In Vivo Potency and Efficacy and Reveals Interactions with the Argonaute-2 PAZ Domain
1个月前
已完结
Systematic Evaluation of Position-Specific Tolerability of Seven Backbone and Ribose Modifications in Fully Chemically Stabilized siRNAs
1个月前
已完结
siRNA Design and GalNAc-Empowered Hepatic Targeted Delivery
1个月前
已完结
Direct cytosolic delivery of siRNA via cell membrane fusion using cholesterol-enriched exosomes
1个月前
已完结
Nonclinical Pharmacokinetics and Absorption, Distribution, Metabolism, and Excretion of Givosiran, the First Approved N-Acetylgalactosamine–Conjugated RNA Interference Therapeutic
2个月前
已完结
RNA interference in the era of nucleic acid therapeutics
2个月前
已完结
Enhancing siRNA efficacy in vivo with extended nucleic acid backbones
2个月前
已完结
RNA-induced silencing complex-bound small interfering RNA is a determinant of RNA interference-mediated gene silencing in mice
2个月前
已关闭
RNA-Induced Silencing Complex-Bound Small Interfering RNA Is a Determinant of RNA Interference-Mediated Gene Silencing in Mice
2个月前
已关闭
First demonstration of miRNA-dependent mRNA decay
3个月前
已完结
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