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55 积分 2021-06-27 加入
Targeting focal adhesion kinase (FAK) in cancer therapy: A recent update on inhibitors and PROTAC degraders
11天前
已完结
Targeting focal adhesion kinase: from molecular mechanisms to next-generation cancer therapeutics
11天前
已完结
Identification of novel and potent PROTACs targeting FAK for non-small cell lung cancer: Design, synthesis, and biological study
11天前
已完结
Development and Characterization of Selective FAK Inhibitors and PROTACs with In Vivo Activity
11天前
已完结
Augmenting Protein Degradation Capacity of PROTAC through Energy Metabolism Regulation and Targeted Drug Delivery
11天前
已完结
Degradation of FAK-targeting by proteolytic targeting chimera technology to inhibit the metastasis of hepatocellular carcinoma
11天前
已完结
A novel FAK-targeted degrader: Design, synthesis, and therapeutic potential against colorectal cancer
11天前
已完结
Structure-guided design of a potent focal adhesion kinase (FAK) degrader via ternary complex modeling and molecular dynamics simulation
11天前
已完结
FAK PROTAC Inhibits Ovarian Tumor Growth and Metastasis by Disrupting Kinase Dependent and Independent Pathways
11天前
已完结
FAK-targeting PROTAC demonstrates enhanced antitumor activity against KRAS mutant non-small cell lung cancer
12天前
已完结
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