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25 积分 2021-06-27 加入
Polycyclic Sulfoximines as New Scaffolds for Drug Discovery
12天前
已完结
Heck versus suzuki palladium catalysed cross-coupling of a vinylboronate ester with aryl halides
19天前
已完结
Discovery of a brain-penetrant fourth-generation EGFR inhibitor to overcome the human triple (L858R/T790 M/C797S) mutation
19天前
已完结
Regioselective Control of the SNAr Amination of 5-Substituted-2,4-Dichloropyrimidines Using Tertiary Amine Nucleophiles
23天前
已完结
Selective addition of amines to 5-trifluoromethyl-2,4-dichloropyrimidine induced by Lewis acids
23天前
已完结
Design, synthesis and biological evaluation of novel 4-aminopiperidine derivatives as SMO/ERK dual inhibitors
23天前
已完结
Synthesis and biological evaluation of pyrimidine derivatives as novel human Pin1 inhibitors
23天前
已完结
Highly Selective Inhibition of Tyrosine Kinase 2 (TYK2) for the Treatment of Autoimmune Diseases: Discovery of the Allosteric Inhibitor BMS-986165
1个月前
已完结
Molecular description of pyrimidine-based inhibitors with activity against FAK combining 3D-QSAR analysis, molecular docking and molecular dynamics
1个月前
已完结
Targeting FAK/PYK2 with SJP1602 for Anti-Tumor Activity in Triple-Negative Breast Cancer
1个月前
已完结