Lv1
30 积分 2023-08-17 加入
Targeting the TNF and TNFR superfamilies in autoimmune disease and cancer
1天前
已完结
Discovery of AK-1690: A Potent and Highly Selective STAT6 PROTAC Degrader
2天前
已完结
Targeting the Hippo pathway in cancer: kidney toxicity as a class effect of TEAD inhibitors?
4个月前
已完结
Discovery of Rezatapopt (PC14586), a First-in-Class, Small-Molecule Reactivator of p53 Y220C Mutant in Development
4个月前
已完结
Elucidating Binding Selectivity in Cyclin-Dependent Kinases (CDKs) 4, 6, and 9: Development of Highly Potent and Selective CDK4/9 Inhibitors
6个月前
已完结
Design and Development of Glucocorticoid Receptor Modulators as Immunology Antibody–Drug Conjugate Payloads
6个月前
已完结
Self-Immolative Carbamate Linkers for CD19-Budesonide Antibody–Drug Conjugates
6个月前
已完结
At a crossroads: how to translate the roles of PI3K in oncogenic and metabolic signalling into improvements in cancer therapy
8个月前
已完结
Discovery of novel chemotype inhibitors targeting Anaplastic Lymphoma Kinase receptor through ligand-based pharmacophore modelling
8个月前
已完结
Fragment-based discovery of novel phenyltriazolyl derivatives as allosteric type-I1/2 ALK inhibitors with promising antitumor effects
8个月前
已完结
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