Lv1
30 积分 2024-05-23 加入
Co-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules
12小时前
待确认
Structure-guided development of chemically tailored peptide binders of RNF43/ZNRF3 to enable versatile design of membrane protein-targeting PROTACs
2个月前
已完结
Pulmonary tuberculosis with appearances of gastric cancer
2个月前
已关闭
A Rational Utilization of High-Throughput Screening Leads to Selective, Orally Bioavailable 1-Benzyl-3-carboxyazetidine Sphingosine-1-phosphate-1 Receptor Agonists
7个月前
已完结
Small Molecule Inhibitors Targeting the “Undruggable” Survivin: The Past, Present, and Future from a Medicinal Chemist’s Perspective
9个月前
已完结
EZH2 PROTACs target EZH2- and FOXM1-associated oncogenic nodes, suppressing breast cancer cell growth
9个月前
已完结
HDAC8 Enhances the Function of HIF‐2α by Deacetylating ETS1 to Decrease the Sensitivity of TKIs in ccRCC
9个月前
已完结
Pan-cancer proteogenomics expands the landscape of therapeutic targets
9个月前
已完结
Dynamic molecular architecture and substrate recruitment of cullin3–RING E3 ligase CRL3KBTBD2
11个月前
已完结
KBTBD4 Cancer Hotspot Mutations Drive Neomorphic Degradation of HDAC1/2 Corepressor Complexes
11个月前
已完结
皖公网安备34019202002308
