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20 积分 2024-05-23 加入
Proteolysis Targeting Chimeras (PROTACs) Based on Promiscuous Kinase Inhibitor Synergistically Induce Cancer Cell Apoptosis Through Multiple Mechanisms
5天前
已完结
EGFR degraders in non‐small‐cell lung cancer: Breakthrough and unresolved issue
6天前
已完结
Disruption of KLHL37-N-Myc complex restores N-Myc degradation and arrests neuroblastoma growth in mouse models
1个月前
已完结
Co-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules
3个月前
已完结
Structure-guided development of chemically tailored peptide binders of RNF43/ZNRF3 to enable versatile design of membrane protein-targeting PROTACs
5个月前
已完结
Pulmonary tuberculosis with appearances of gastric cancer
5个月前
已关闭
A Rational Utilization of High-Throughput Screening Leads to Selective, Orally Bioavailable 1-Benzyl-3-carboxyazetidine Sphingosine-1-phosphate-1 Receptor Agonists
11个月前
已完结
Small Molecule Inhibitors Targeting the “Undruggable” Survivin: The Past, Present, and Future from a Medicinal Chemist’s Perspective
1年前
已完结
EZH2 PROTACs target EZH2- and FOXM1-associated oncogenic nodes, suppressing breast cancer cell growth
1年前
已完结
HDAC8 Enhances the Function of HIF‐2α by Deacetylating ETS1 to Decrease the Sensitivity of TKIs in ccRCC
1年前
已完结
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