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90 积分 2024-12-31 加入
Discovery and Evaluation of N -Arylindole-Based GluN2B-NMDAR Antagonists with Reduced Cardiotoxicity for the Treatment of Ischemic Stroke
26天前
已完结
Discovery of 1-Difluoromethyl-3-(3-cyanophenyl)-6-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrazin-8-(7H)-one as a Potent P2Y1 Antagonist for the Treatment of Ischemic Stroke and Myocardial Infarction
26天前
已完结
Design, synthesis, and biological evaluation of 2-(naphthalen-1-yloxy)-N-phenylacetamide derivatives as TRPM4 inhibitors for the treatment of prostate cancer
1个月前
已完结
Discovery of HZS60 as a Novel Brain Penetrant NMDAR/TRPM4 Interaction Interface Inhibitor with Improved Activity and Pharmacokinetic Properties for the Treatment of Cerebral Ischemia
1个月前
已完结
Supporting an integrated QTc risk assessment using the hERG margin distributions for three positive control agents derived from multiple laboratories and on multiple occasions
2个月前
已完结
An Analysis of the Relationship Between Preclinical and Clinical QT Interval-Related Data
2个月前
已完结
Alkylation of isatins with trichloroacetimidates
3个月前
已完结
The Antiestrogen Tamoxifen Blocks the Delayed Rectifier Potassium Current, IKr, in Rabbit Ventricular Myocytes
3个月前
已关闭
P-Stereogenic Phosphorus Ligands in Asymmetric Catalysis
5个月前
已完结
Phosphate moiety in FDA‐approved pharmaceutical salts and prodrugs
8个月前
已完结
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