Lv11
78 积分 2024-01-27 加入
Novel Acyl Thiourea-Based Hydrophobic Tagging Degraders Exert Potent Anti-Influenza Activity through Two Distinct Endonuclease Polymerase Acidic-Targeted Degradation Pathways
4小时前
待确认
Single-step fluorescent probes to detect decrotonylation activity of HDACs through intramolecular reactions
1个月前
已完结
Discovery of Novel ERα and Aromatase Dual-Targeting PROTAC Degraders to Overcome Endocrine-Resistant Breast Cancer
4个月前
已完结
Design, Synthesis and Anti-Inflammatory Evaluation of 3-Substituted 5-Amidobenzoate Derivatives as Novel P2Y14 Receptor Antagonists via Structure-Guided Molecular Hybridization
4个月前
已完结
鉴定具有微管蛋白抑制活性的新型双靶点雌激素受体 α 降解剂，用于治疗内分泌耐药性乳腺癌
5个月前
已完结
新型酰基硫脲基疏水标签降解剂通过两种不同的核酸内切酶聚合酶酸性靶向降解途径发挥有效的抗流感活性
5个月前
已完结
发现新型 ERα 和芳香酶双靶向 PROTAC 降解剂以克服内分泌耐药乳腺癌
5个月前
已完结
新型 Hsp90 靶向 PROTAC：增强与顺铂联合治疗宫颈癌的协同作用
5个月前
已完结
Discovery of Chiral 1,4-Diarylazetidin-2-one-Based Hydroxamic Acid Derivatives as Novel Tubulin Polymerization Inhibitors with Histone Deacetylase Inhibitory Activity
6个月前
已完结
Discovery of Novel Diaryl-Substituted Fused Heterocycles Targeting Katanin and Tubulin with Potent Antitumor and Antimultidrug Resistance Efficacy
6个月前
已完结
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