Lv1
30 积分 2024-02-16 加入
Design, Synthesis, and Biological Evaluation of Novel Diaminopyrimidine Macrocycles as Fourth Generation Reversible EGFR Inhibitors That Overcome Clinical Resistance to Osimertinib Mediated by C797S Mutation
1个月前
已完结
The new opportunities in medicinal chemistry of fourth-generation EGFR inhibitors to overcome C797S mutation
1个月前
已完结
Specific removal of o-methoxybenzyl protection by DDQ oxidation
2个月前
已完结
Regioselective manipulation of hydroxyl groups via organotin derivatives
2个月前
已完结
Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor
4个月前
已完结
Strategic use of conformational bias and structure based design to identify potent JAK3 inhibitors with improved selectivity against the JAK family and the kinome
4个月前
已完结
Inhibition of JAK3 with a novel, selective and orally active small molecule induces therapeutic response in T-cell malignancies
5个月前
已完结
Tyrosine Kinase Inhibitor–Associated Cardiovascular Toxicity in Chronic Myeloid Leukemia
6个月前
已完结
Diagnosis, management and prevention of drug-induced liver injury
6个月前
已完结
Cardiovascular Safety of Tyrosine Kinase Inhibitors: With a Special Focus on Cardiac Repolarisation (QT Interval)
6个月前
已关闭
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