Lv11
30 积分 2023-04-06 加入
Benzalkonium chloride disrupts human placental progesterone synthesis via locking NAD+ pocket in 3β-Hydroxysteroid dehydrogenase 1 and rat homolog: docking evidence and 3D-QSAR, and experiment risk assessment
45分钟前
求助中
Salicylate esters inhibit human and rat 11β-Hydroxysteroid dehydrogenase type 2: Mechanistic insights from enzyme kinetics, SPR, and molecular modeling
48分钟前
求助中
Structure-activity relationship of per- and Polyfluoroalkyl substances as inhibitors of human and rat 17β-Hydroxysteroid dehydrogenase 3
18天前
已完结
Halogenated phenolic disinfectants suppress 11β-hydroxysteroid dehydrogenase 2 activity in human and rat models: Experimental and computational evidence
3个月前
已完结
Halogenated phenolic disinfectants suppress 11β-hydroxysteroid dehydrogenase 2 activity in human and rat models: Experimental and computational evidence
4个月前
已关闭
Interleukin-2 receptor γ blocks the development of Leydig cells from stem/progenitor cells in male rats via JAK1-STAT3 pathway and GSDMD-mediated pyroptosis
4个月前
已完结
Hydrophobicity-driven inhibition of human and rat 11β-hydroxysteroid dehydrogenase 2 by isothiazolinone biocides: Insights from enzyme kinetics and SPR interactions
4个月前
已完结
Inhibition of brain human steroid 5α-reductase 1 by dithiocarbamates: A Comprehensive enzymatic and structural analysis
5个月前
已关闭
Benzalkonium disinfectants as emerging endocrine disruptors: Inhibition of 11β-Hydroxysteroid dehydrogenase 2 in human and rat models via steric and hydrophobic mechanisms: SPR and docking and enzymatic analysis
6个月前
已完结
Biphasic inhibition of human and rat steroid 5α-reductase 1 for Neurosteroid synthesis by mid-chain Dialkyldimethylammonium compounds (C8-C14): Kinetic, SPR binding, computational insights, and implications for environmental toxicology
7个月前
已完结
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