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2 积分 2022-05-02 加入
Discovery of highly potent and selective KRASG12C degraders by VHL-recruiting PROTACs for the treatment of tumors with KRASG12C-Mutation
26天前
已完结
Discovery and Characterization of RP04340 : A Highly Potent and Orally Active Pan-KRAS PROTAC Degrader
26天前
已完结
Design, synthesis and biological evaluation of KRASG12C-PROTACs
26天前
已完结
Stage-specific activity of the Leishmania major CRK3 kinase and functional rescue of a Schizosaccharomyces pombe cdc2 mutant
29天前
已完结
Novel fragment-based QSAR modeling and combinatorial design of pyrazole-derived CRK3 inhibitors as potent antileishmanials
1个月前
已完结
ZJK-807: A Selective PROTAC Degrader of KRASG12D Overcoming Resistance in Pancreatic Cancer
1个月前
已完结
KRASG12D selective VHL-PROTAC with sparing KRASWT and other KRAS mutants
1个月前
已完结
Discovery of KRAS-G12D degraders via exploration of various E3 ligases
1个月前
已完结
Discovery and Characterization of RP04340 : A Highly Potent and Orally Active Pan-KRAS PROTAC Degrader
1个月前
已完结
Development and Preclinical Evaluation of Radiolabeled Covalent G12C-Specific Inhibitors for Direct Imaging of the Oncogenic KRAS Mutant
1个月前
已完结
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