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Abstract 3095: Comparative analysis of WRN inhibitors HRO761 and VVD-133214 in a cancer cell panel: insights into MSI status-dependent drug responses
2天前
求助中
925MO First-in-human phase I/Ib study of the oral Werner (WRN) helicase inhibitor HRO761 in patients (pts) with microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) advanced solid tumors: Interim safety and efficacy analysis from HRO761 single agent dose escalation
2天前
求助中
Design and Discovery of Preclinical Candidate LYG-409 as a Highly Potent and Selective GSPT1 Molecular Glue Degraders
3天前
已完结
Targeting CDK2 for cancer therapy
1个月前
已完结
Inhibitors and PROTACs of CDK2: challenges and opportunities
1个月前
已完结
Cyclin-dependent kinase 2 (CDK2) inhibitors and others novel CDK inhibitors (CDKi) in breast cancer: clinical trials, current impact, and future directions
1个月前
已完结
Cyclin-dependent protein kinases and cell cycle regulation in biology and disease
1个月前
已完结
Benchmarking Methods for PROTAC Ternary Complex Structure Prediction
1个月前
已完结
Design, synthesis, and structure−activity relationship studies of triazolo-pyrimidine derivatives as WRN inhibitors for the treatment of MSI tumors
1个月前
已完结
Development of PROTACs using computational approaches
1个月前
已完结
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