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6 积分 2024-08-26 加入
Inavolisib-Based Therapy in PIK3CA -Mutated Advanced Breast Cancer
9天前
已完结
Beyond Cytotoxic Payloads for Antibody Drug Conjugates─A Medicinal Chemistry Perspective
15天前
已完结
Design, Synthesis, Formulation, and Bioevaluation of Trisubstituted Triazines as Highly Selective mTOR Inhibitors for the Treatment of Human Breast Cancer
15天前
已完结
The Identification of Potent, Selective, and Orally Available Inhibitors of Ataxia Telangiectasia Mutated (ATM) Kinase: The Discovery of AZD0156 (8-{6-[3-(Dimethylamino)propoxy]pyridin-3-yl}-3-methyl-1-(tetrahydro-2H-pyran-4-yl)-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one)
15天前
已完结
A Novel Dual ATM/DNA-PK Inhibitor, XRD-0394, Potently Radiosensitizes and Potentiates PARP and Topoisomerase I Inhibitors
16天前
已完结
Discovery and Pharmacological Characterization of a Dual-Acting 2-Amino-3-Cyanopyridine Inhibitor Targeting Microtubule Polymerization and GAK
28天前
已完结
Structural basis of human γ-secretase inhibition by anticancer clinical compounds
28天前
已完结
Unexpected Reactivity of 1,3,4-Thiadiazole- N -oxides with Strained Alkynes Enables Enhanced Antibody Loading
30天前
已完结
Evaluation of Cellular Targeting by Fab′ vs Full-Length Antibodies in Antibody–Nanoparticle Conjugates (ANCs) Using CD4 T-cells
30天前
已完结
Blood–brain-barrier-crossing lipid nanoparticles for mRNA delivery to the central nervous system
1个月前
已完结
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