Lv11
90 积分 2024-09-24 加入
Discovery of Novel Imidazothiazole-Based Hydroxamic Acid Derivatives as Potent Indoleamine 2,3-Dioxygenase 1 and Histone Deacetylase 6 Dual Inhibitors
12小时前
待确认
First CAR T for solid tumors
1个月前
已完结
Targeting STING elicits GSDMD-dependent pyroptosis and boosts anti-tumor immunity in renal cell carcinoma
2个月前
已完结
Therapeutic horizons in the development of PROTAC-based EZH2 inhibitors: recent achievements, comparative analysis, and future perspectives
6个月前
已完结
Mechanistic insights into Wnt–β-catenin pathway activation and signal transduction
6个月前
已完结
Harnessing the E3 Ligase KEAP1 for Targeted Protein Degradation
6个月前
已完结
Abstract P5-04-18: ARV-471, an oral estrogen receptor PROTAC degrader for breast cancer
7个月前
已完结
Discovery of Small-Molecule Inhibitors of the PD-1/PD-L1 Axis That Promote PD-L1 Internalization and Degradation
7个月前
已完结
Targeting both death and paracaspase domains of MALT1 with antisense oligonucleotides overcomes resistance to immune-checkpoint inhibitors
7个月前
已完结
Novel therapeutic strategies targeting resistance mechanisms in hematologic malignancies: from BCL2 inhibition to immunomodulatory approaches
7个月前
已完结
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