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80 积分 2024-09-24 加入
Targeting STING elicits GSDMD-dependent pyroptosis and boosts anti-tumor immunity in renal cell carcinoma
22天前
已完结
Therapeutic horizons in the development of PROTAC-based EZH2 inhibitors: recent achievements, comparative analysis, and future perspectives
4个月前
已完结
Mechanistic insights into Wnt–β-catenin pathway activation and signal transduction
4个月前
已完结
Harnessing the E3 Ligase KEAP1 for Targeted Protein Degradation
4个月前
已完结
Abstract P5-04-18: ARV-471, an oral estrogen receptor PROTAC degrader for breast cancer
5个月前
已完结
Discovery of Small-Molecule Inhibitors of the PD-1/PD-L1 Axis That Promote PD-L1 Internalization and Degradation
5个月前
已完结
Targeting both death and paracaspase domains of MALT1 with antisense oligonucleotides overcomes resistance to immune-checkpoint inhibitors
5个月前
已完结
Novel therapeutic strategies targeting resistance mechanisms in hematologic malignancies: from BCL2 inhibition to immunomodulatory approaches
5个月前
已完结
Opportunities and challenges of targeting cGAS–STING in cancer
5个月前
已完结
Enhancing immunotherapy in cancer by targeting emerging immunomodulatory pathways
5个月前
已完结