Lv5
1158 积分 2024-10-18 加入
Discovery of Aficamten (CK-274), a Next-Generation Cardiac Myosin Inhibitor for the Treatment of Hypertrophic Cardiomyopathy
2天前
已完结
Design, Structural Analysis, Hirshfeld Surface Study, and Molecular Docking of an o-Dianisidine-Based Compound for Pharmaceutical Applications
12天前
已完结
Conformational Restriction Enables Discovering a Series of Chroman Derivatives as Potent and Selective NaV1.8 Inhibitors with Improved Pharmacokinetic Properties
22天前
已完结
L-Proline-Catalyzed Knoevenagel Condensation: A Facile, Green Synthesis of (E)-Ethyl 2-Cyano-3-(1H-indol-3-yl)acrylates and (E)-3-(1H-Indol-3-yl)acrylonitriles
1个月前
已完结
Structure of mitochondrial pyruvate carrier and its inhibition mechanism
1个月前
已完结
Differential state-dependent Nav1.8 inhibition by suzetrigine, LTGO-33, and A-887826
1个月前
已关闭
Differential state-dependent Nav1.8 inhibition by suzetrigine, LTGO-33, and A-887826
2个月前
已关闭
Pharmacologic Characterization of LTGO-33, a Selective Small Molecule Inhibitor of the Voltage-Gated Sodium Channel NaV1.8 with a Unique Mechanism of Action
2个月前
已完结
Humanized cerebral organoids-based ischemic stroke model for discovering of potential anti-stroke agents
2个月前
已完结
Structural basis for human Cav3.2 inhibition by selective antagonists
3个月前
已完结
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