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46 积分 2024-04-03 加入
Rational Design of Dual Degraders by Incorporating Molecular Glue Structural Features into PROTAC Degraders
16天前
已完结
Discovery of BWA-522, a First-in-Class and Orally Bioavailable PROTAC Degrader of the Androgen Receptor Targeting N-Terminal Domain for the Treatment of Prostate Cancer
16天前
已完结
Discovery of a Novel Non-invasive AR PROTAC Degrader for the Topical Treatment of Androgenetic Alopecia
16天前
已完结
Design, Synthesis, and Activity Evaluation of BRD4 PROTAC Based on Alkenyl Oxindole-DCAF11 Pair
1个月前
已完结
Synthesis of an RBM39 Degrader That Downregulates CEP192 and Induces Disorganized Spindle Structures
2个月前
已完结
Discovery and Optimization of Potent PROTAC Degraders of Phosphoinositide 3-Kinase with Significant in Vivo Anticancer Efficacy
4个月前
已完结
α-Synuclein pathology as a target in neurodegenerative diseases
7个月前
已完结
PNPLA3 as a therapeutic target for fatty liver disease: the evidence to date
7个月前
已完结
Selective and Potent Molecular Glue Degraders for NIMA‐Related Kinase 7
7个月前
已完结
Myeloperoxidase: Molecular Mechanisms of Action and Their Relevance to Human Health and Disease
9个月前
已完结
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