Lv3
228 积分 2023-08-03 加入
Examining P-gp efflux kinetics guided by the BDDCS – Rational selection of in vitro assay designs and mathematical models
2天前
已完结
Population Pharmacokinetics of Sotorasib in Healthy Subjects and Advanced Solid Tumor Patients Harboring a KRASG12C Mutation from Phase 1 and Phase 2 Studies
1个月前
已完结
Prediction of human drug clearance from animal data: Application of the rule of exponents and ‘fu corrected intercept method’ (FCIM)
3个月前
已完结
Rare oncology therapeutics: review of clinical pharmacology package of drug approvals (2019–2023) by US FDA, best practices and recommendations
4个月前
已完结
Pharmacokinetic and Pharmacodynamic Modeling of siRNA Therapeutics - a Minireview
4个月前
已完结
Application of Model‐Informed Drug Development in Dose Selection and Optimization for siRNA Therapies
4个月前
已完结
Endpoint Exposure‐Response Analyses in the Presence of Concurrent Dose Modification During Clinical Trials
4个月前
已完结
Strategies for successful dose optimization in oncology drug development: a practical guide
7个月前
已完结
Combination of the MTA-Cooperative PRMT5 Inhibitor BMS-986504 and KRAS Inhibitors is an Effective Treatment Strategy for MTAP-Deleted KRAS-Mutant Pancreatic Cancer
7个月前
已完结
Early Decision Making in a Randomized Phase II Trial of Atezolizumab in Biliary Tract Cancer Using a Tumor Growth Inhibition‐Survival Modeling Framework
7个月前
已完结
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