Lv3
316 积分 2023-09-22 加入
Property- and structure-guided discovery of a tetrahydroindazole series of interleukin-2 inducible T-cell kinase inhibitors
7天前
已完结
STAT6 Activation in Ulcerative Colitis: A New Target for Prevention of IL-13-Induced Colon Epithelial Cell Dysfunction
13天前
已完结
Tetrahydroindazoles as Interleukin-2 Inducible T-Cell Kinase Inhibitors. Part II. Second-Generation Analogues with Enhanced Potency, Selectivity, and Pharmacodynamic Modulation in Vivo
27天前
已完结
Inhibition of the kinase ITK in a mouse model of asthma reduces cell death and fails to inhibit the inflammatory response
27天前
已完结
Discovery of Potent and Highly Selective Interleukin-2-Inducible T-Cell Kinase Degraders with In Vivo Activity
1个月前
已完结
A Comprehensive Review of Marketed KRAS Inhibitors and Degraders: Challenges and Opportunities
1个月前
已完结
Discovery and Characterization of RP03707: A Highly Potent and Selective KRASG12D PROTAC
1个月前
已完结
ZJK-807: A Selective PROTAC Degrader of KRASG12D Overcoming Resistance in Pancreatic Cancer
1个月前
已完结
Discovery and Characterization of RP04340 : A Highly Potent and Orally Active Pan-KRAS PROTAC Degrader
1个月前
已完结
Crystal structure of the N-terminal domain of MtClpC1 in complex with the anti-mycobacterial natural peptide Lassomycin
1个月前
已完结
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