Lv4
438 积分 2023-09-22 加入
Computational insights into mutation-induced binding changes in Bruton’s Tyrosine Kinase with non-covalent inhibitors
25天前
已完结
Selective CDK2 Degradation via Noncanonical Recruitment
27天前
已完结
Design of Novel Exatecan-Amide Linker-Payloads for the Development of Stable, Low-Aggregating, and Highly Efficacious Antibody-Drug Conjugates
29天前
已完结
Pharmacokinetic characterization of BMS‐936561, an anti‐CD70 antibody‐drug conjugate, in preclinical animal species and prediction of its pharmacokinetics in humans
1个月前
已完结
Discovery of Novel N -Linked Camptothecin Linker-Payloads to Access Antibody–Drug Conjugates with High Target-Mediated In Vivo Efficacy
1个月前
已完结
Exatecan Payload-Based Antibody-Drug Conjugates with a Short Hydrophilic Cleavable Linker
1个月前
已完结
Design of Novel Exatecan-Amide Linker-Payloads for the Development of Stable, Low-Aggregating, and Highly Efficacious Antibody-Drug Conjugates
1个月前
已完结
Systematic Evaluation of Maleimide Spacer Impact on Drug-Linker Deconjugation in Antibody-Drug Conjugates Ex Vivo and In Vivo
1个月前
已完结
A Two-Step Immunocapture LC/MS/MS Assay for Plasma Stability and Payload Migration Assessment of Cysteine–Maleimide-Based Antibody Drug Conjugates
1个月前
已完结
An Enzymatically Cleavable Tripeptide Linker for Maximizing the Therapeutic Index of Antibody-Drug Conjugates
1个月前
已完结
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