Lv4
560 积分 2023-04-13 加入
Crystal Structure of NLRP3 NACHT Domain With an Inhibitor Defines Mechanism of Inflammasome Inhibition
2个月前
已完结
Discovery of NP3-253, a Potent Brain Penetrant Inhibitor of the NLRP3 Inflammasome
2个月前
已完结
Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis
3个月前
已完结
Chemical remodeling of a cellular chaperone to target the active state of mutant KRAS
4个月前
已完结
Discovery of Daraxonrasib (RMC-6236), a Potent and Orally Bioavailable RAS(ON) Multi-selective, Noncovalent Tri-complex Inhibitor for the Treatment of Patients with Multiple RAS-Addicted Cancers
4个月前
已完结
Association of Combination of Conformation-Specific KIT Inhibitors With Clinical Benefit in Patients With Refractory Gastrointestinal Stromal Tumors
4个月前
已完结
Multiple Regulatory Domains of IRF-5 Control Activation, Cellular Localization, and Induction of Chemokines That Mediate Recruitment of T Lymphocytes
5个月前
已关闭
A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus
5个月前
已完结
Crystal structure of IRF-3 reveals mechanism of autoinhibition and virus-induced phosphoactivation
5个月前
已完结
Molecular characterization of latent GDF8 reveals mechanisms of activation
5个月前
已完结
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