Lv3
324 积分 2023-07-11 加入
Identification of a Novel Protein Phosphatase 2A Activator, PPA24, as a Potential Therapeutic for FOLFOX-Resistant Colorectal Cancer
9小时前
已完结
Highly Selective PTK2 Proteolysis Targeting Chimeras to Probe Focal Adhesion Kinase Scaffolding Functions
1个月前
已完结
Identification of a Potent and Selective Focal Adhesion Kinase Proteolysis Targeting Chimera: Targeting Noncatalytic Functions of Focal Adhesion Kinase to Facilitate Antitumor Immunity
1个月前
已完结
Property-Based Optimization of Cereblon-Based Molecular Glue Degraders
1个月前
已完结
Design and Synthesis of Novel Cereblon Binders for Use in Targeted Protein Degradation
1个月前
已完结
Leveraging Supercritical Fluid Chromatography for Monitoring the Formation of Methanol Adducts of AR-LDD Antagonist BMS-986409 in Spray-Dried Dispersion Materials
1个月前
已完结
Identification of a Potent and Selective CDK9 Degrader as a Targeted Therapeutic Option for the Treatment of Small-Cell Lung Cancer
1个月前
已完结
Evaluation of Cereblon-Directing Warheads for the Development of Orally Bioavailable PROTACs
1个月前
已完结
Discovery and Preclinical Pharmacology of NX-2127, an Orally Bioavailable Degrader of Bruton’s Tyrosine Kinase with Immunomodulatory Activity for the Treatment of Patients with B Cell Malignancies
1个月前
已完结
Discovery of KT-413, a Targeted Protein Degrader of IRAK4 and IMiD Substrates Targeting MYD88 Mutant Diffuse Large B-Cell Lymphoma
1个月前
已完结