Lv13
90 积分 2025-06-30 加入
Discovery of Highly Potent Phthalazinone Derivatives as PARP14 Inhibitors: From Structure-Based Virtual Screening to In Vivo Pharmacodynamic Activity
8小时前
已完结
JYP0322, a highly selective and brain-penetrant ROS1 inhibitor, overcomes ROS1 resistance mutation in NSCLC: The first-in-human phase 1 trial
1天前
已完结
Kinase Targets and Drug Discovery
1天前
已关闭
Targeting the Interaction of NRF2 and β-TrCP with Molecular Glues
1天前
已完结
Discovery of Naphthyridinone Derivatives as Selective and Potent PKMYT1 Inhibitors with Antitumor Efficacy
1天前
已完结
Discovery of Naphthyridinone Derivatives as Selective PKMYT1/WEE1 Dual Inhibitors for Cancer Therapy
2天前
已完结
Structure Merging Approach Leads to New Dual Potent and Selective USP25/USP28 Inhibitors
2天前
已完结
Accurate PROTAC-targeted degradation prediction with DegradeMaster
18天前
已关闭
Rational Prediction of PROTAC-compatible Protein-Protein Interfaces by Molecular Docking
18天前
已完结
Discovery of a miniaturized PROTAC with potent activity and high selectivity
18天前
已完结
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