Lv4
578 积分 2021-03-19 加入
Mechanism of hypoxia-specific cytotoxicity of procaspase-3 fused with a VHL-mediated protein destruction motif of HIF-1α containing Pro564
5天前
已关闭
Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O2-Regulated Prolyl Hydroxylation
6天前
已完结
The combination of hypoxia-response enhancers and an oxygen-dependent proteolytic motif enables real-time imaging of absolute HIF-1 activity in tumor xenografts
8天前
已完结
Amino acid supplementation enhances in vivo efficacy of lipid nanoparticle–mediated mRNA delivery in preclinical models
8天前
已完结
In vivo endosomal escape assay identifies mechanisms for efficient hepatic LNP delivery
8天前
已完结
A logic-gated trispecific engager enhances macrophage killing of cancer cells in solid tumors
8天前
已完结
Prodrug-tethered lipid nanoparticles for synergistic messenger RNA cancer immunotherapy
8天前
已完结
‘Tripod-like’ lung-targeting (LuT) lipids for highly efficient and selective LNPs for gene delivery and editing
9天前
已完结
Crosslinked ionizable lipids reprogram dendritic cell metabolism for potent mRNA vaccination
9天前
已完结
Artificial intelligence-guided design of LNPs for in vivo targeted mRNA delivery via analysis of the spatial conformation of ionizable lipids
9天前
已完结
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