Lv5
938 积分 2023-03-30 加入
Utilizing Molecular Dynamics and Mechanistic Pharmacokinetic Studies in the Design of Selective CDK2 Inhibitors
9天前
已完结
Novel drug targets in 2025
17天前
已完结
Synthesis, gene silencing activity, thermal stability, and serum stability of siRNA containing four (S)-5′-C-aminopropyl-2′-O-methylnucleosides (A, adenosine; U, uridine; G, guanosine; and C, cytidine)
21天前
已完结
Reduced Genotoxicity Testing Is Possible for Noncoding Oligonucleotide-Based Therapeutics Containing Well-Characterized Modifications: A European Regulatory Perspective
23天前
已完结
2558-P: A Versatile siRNA Delivery Platform Enabling Dual-Targeting and Multitissue Gene Silencing for Treatment of Metabolic Disorders
24天前
已完结
1102-OR: Adipose-Targeted ALK7 siRNA Synergizes with Tirzepatide to Reduce Fat Mass while Preserving Lean Mass in Diet-Induced Obese Mice
24天前
已完结
The Approval of Redemplo for Familial Chylomicronemia Syndrome and the Many Flavors of GalNAc-Oligonucleotides
24天前
已完结
A Long‐Term Human Liver Spheroid Model for Assessing Silencing and Durability of GalNAc ‐Conjugated siRNAs
28天前
已完结
High-dose biologics and bioconjugates delivery: Integrating molecular optimization with device design and routes of administration
28天前
已完结
Harnessing TfR1 for Cross-Species Systemic Delivery of siRNAs to Deep Brain Regions Using Single-Domain Antibodies
29天前
已完结
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