Lv61
2984 积分 2022-10-24 加入
Application of Bioisosteres in the Design and Discovery of FDA-Approved Drugs and Advanced Clinical Candidates
7天前
已完结
Mechanistic dissection of SMARCA2/4 molecular glues reveals programmable switching between DCAF16 and FBXO22
11天前
已完结
Fragment-Based Discovery and Structure-Led Optimization of MSC778, the First Potent, Selective, and Orally Bioavailable FEN1 Inhibitor
26天前
已完结
Synthetic Approaches to the New Drugs Approved During 2024
1个月前
已完结
Lessons learned in linking PROTACs from discovery to the clinic
1个月前
已完结
New perspectives for targeting therapy in ALK-positive human cancers
1个月前
已完结
ALK-positive lung cancer: a moving target
1个月前
已完结
Targeting Multiple KRAS Mutations with High-Affinity Macrocyclic Inhibitors: From Discovery to Preclinical Validation
2个月前
已完结
Antibody-Mediated Delivery of BRM/BRG1 Protein Degraders Affords Strong Antitumor Efficacy in Multiple BRM-Dependent Non-Small Cell Lung Cancer Xenograft Models
2个月前
已完结
Optimization of METTL3 Inhibitors for the Treatment of Solid Tumors and AML
3个月前
已完结
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