Lv6
2790 积分 2020-09-19 加入
Programmable DNA Origami-Based Protease Device for Precise and Direct Proteins Degradation
8天前
已完结
Recent advances in the development of acridine-based hybrids with antiproliferative activity
19天前
已完结
Harnessing FBXO31 with terminal amide-functionalized molecules for targeted protein degradation
1个月前
已完结
Harnessing the SPOP E3 Ubiquitin Ligase via a Bridged Proteolysis Targeting Chimera (PROTAC) Strategy for Targeted Protein Degradation
1个月前
已完结
Rational Design of Dual-Target Molecules via a Fragment-Merging Strategy: TGR5 Agonism and SSTR5 Antagonism
1个月前
已完结
Construction of PROTAC Library via Liquid-Phase Synthesis Enabled by a Hydrophobic Tag
1个月前
已完结
Design, Synthesis, and Antitumor Activity Evaluation of 2-Arylmethoxy-4-(2,2′-dihalogen-substituted biphenyl-3-ylmethoxy) Benzylamine Derivatives as Potent PD-1/PD-L1 Inhibitors
1个月前
已完结
New PROTAC Designs for Targeted Protein Degradation in 2021–2025: Novel E3 Ligases and Pre-PROTACs
1个月前
已完结
In Vivo Half-Life of a Protein Is a Function of Its Amino-Terminal Residue
2个月前
已完结
Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability
2个月前
已完结
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