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1438 积分 2024-12-24 加入
Beyond CRBN and VHL: DCAF16-Recruiting Degraders from Rational Design to Clinical Translation
1天前
已完结
Synthetic Lethality through the Lens of Medicinal Chemistry
2天前
已完结
Targeting of PI3K/AKT signaling and DNA damage response in acute myeloid leukemia: a novel therapeutic strategy to boost chemotherapy response and overcome resistance
2天前
已完结
Molecular mechanisms involved in DNA repair in human cancers: An overview of PI3k/Akt signaling and PIKKs crosstalk
2天前
已完结
ORM-6151: A First-in-Class, Anti-CD33 Antibody-Enabled GSPT1 Degrader for AML
3天前
已关闭
GSPT1 degraders: research progress, development strategies and challenges
3天前
已完结
Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15
3天前
已完结
Optimization of Potent Ligands for the E3 Ligase DCAF15 and Evaluation of Their Use in Heterobifunctional Degraders
3天前
已完结
Novel antibody-drug conjugates targeting EphA3 in tumours and the tumour microenvironment
4天前
已完结
Application of Bioisosteres in the Design and Discovery of FDA-Approved Drugs and Advanced Clinical Candidates
4天前
已完结
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