Lv3
240 积分 2024-12-31 加入
Design of Novel Exatecan-Amide Linker-Payloads for the Development of Stable, Low-Aggregating, and Highly Efficacious Antibody-Drug Conjugates
11天前
已完结
Discovery of Novel N-Linked Camptothecin Linker-Payloads to Access Antibody-Drug Conjugates with High Target-Mediated In Vivo Efficacy
11天前
已完结
β-glucuronidase-triggered ortho-hydroxyl-mediated cyclization strategy for the efficient delivery of phenolic payloads in antibody-drug conjugates
17天前
已完结
Medoxomil Prodrug Strategies
18天前
已完结
Targeted Rheumatoid Arthritis Therapy Using a Smart Nitric Oxide‐Responsive JAK Inhibition
24天前
已完结
Enzyme-Agnostic Lysosomal Screen Identifies New Legumain-Cleavable ADC Linkers
29天前
已完结
TUB-010, a Novel Anti-CD30 Antibody–Drug Conjugate Based on Tub-Tag Technology, Widens the Therapeutic Window by Reducing Toxicity While Maintaining High Efficacy
1个月前
已完结
DB-1303, a HER2-targeting ADC with a novel DNA topoisomerase I inhibitor, demonstrates a promising safety profile and anti-tumor efficacy with differentiation from DS-8201a
1个月前
已完结
Abstract 5757: Exatecan payload-based antibody-drug conjugates with a short hydrophilic beta-glucuronidase cleavable linker
1个月前
已完结
Combinatorial strategies to target RAS-driven cancers
1个月前
已完结