Lv0
0 积分 2024-04-27 加入
Discovery of Pyrazolo[1,5-a]pyridine Derivatives as Potent and Selective PI3Kγ/δ Inhibitors
1天前
待确认
The response to anti–PD-1 and anti–LAG-3 checkpoint blockade is associated with regulatory T cell reprogramming
1天前
已完结
Discovery of Daraxonrasib (RMC-6236), a Potent and Orally Bioavailable RAS(ON) Multi-selective, Noncovalent Tri-complex Inhibitor for the Treatment of Patients with Multiple RAS-Addicted Cancers
7天前
已完结
Dual PI3K/mTOR inhibition is required to combat resistance to CDK4/6 inhibitor and endocrine therapy in PIK3CA -mutant breast cancer
12天前
已完结
Preclinical characterization of TOS-358, a potent and selective covalent inhibitor of wild-type and mutant PI3Kα with superior anticancer activity
13天前
已完结
Formate Supplementation Enhances Antitumor CD8+ T-cell Fitness and Efficacy of PD-1 Blockade
1个月前
已完结
Fasting-mimicking diet-enriched Bifidobacterium pseudolongum suppresses colorectal cancer by inducing memory CD8 + T cells
3个月前
已完结
Deubiquitination of aryl hydrocarbon receptor by USP21 negatively regulates T helper 17 cell differentiation
4个月前
已完结
Cross-reactivity between tumor MHC class I–restricted antigens and an enterococcal bacteriophage
7个月前
已完结
Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors
7个月前
已完结