Lv3
234 积分 2025-12-04 加入
Rational design of VHL-recruiting KRASG12C proteolysis-targeting chimeras based on molecular dynamics simulation
17天前
已完结
Translational Research on the Oral Delivery of the Cytotoxic PROTAC Molecule via Tumor-Targeting Prodrug Strategy for Triple-Negative Breast Cancer Treatment
1个月前
已完结
PROTAC delivery in tumor immunotherapy: Where are we and where are we going?
1个月前
已完结
Nanoenabled Strategies Enhancing PROTACs for Cancer Therapy
1个月前
已完结
Proteolysis-targeting chimera (PROTAC) nanomedicines toward cancer treatment: From synthesis to therapeutic delivery
1个月前
已完结
KRASG12D selective VHL-PROTAC with sparing KRASWT and other KRAS mutants
2个月前
已完结
Establishment and validation of a sensitive LC–MS/MS method for the quantification of KRASG12C protein PROTAC molecule LC‐2 in rat plasma and its application to in vivo pharmacokinetic studies of LC‐2 PEGylated liposomes
2个月前
已完结
Discovery of highly potent and selective KRASG12C degraders by VHL-recruiting PROTACs for the treatment of tumors with KRASG12C-Mutation
2个月前
已完结
Rational design of VHL-recruiting KRASG12C proteolysis-targeting chimeras based on molecular dynamics simulation
2个月前
已完结
Discovery of Pyrazoloquinazoline Analogues as Orally Bioavailable KRAS-G12D Inhibitors
4个月前
已完结
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