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8 积分 2025-12-03 加入
Discovery of Novel Potent Triple IKZF1/2/3 Degraders for the Treatment of Hematological Cancers
1天前
待确认
Rational design of VHL-recruiting KRASG12C proteolysis-targeting chimeras based on molecular dynamics simulation
1天前
已完结
Structure-Based Discovery of Novel, Highly Potent VEGFR2 Inhibitors with a Naphthalene Scaffold against a Broad Range of Solid Tumors
1天前
已完结
The design, synthesis and bioactivity evaluation of novel androgen receptor degraders based on hydrophobic tagging
30天前
已完结
Hydrophobic tag tethering degrader as a promising paradigm of protein degradation: Past, present and future perspectives
1个月前
已完结
Identification of novel SARS-CoV-2 3CLpro inhibitors by molecular docking, in vitro assays, molecular dynamics simulations and DFT analyses
1个月前
已关闭
Identification of novel non-covalent Mpro inhibitors against SARS-CoV-2 by the computational and experimental approaches
1个月前
已完结
Design, synthesis, and biological activity of human glutaminyl cyclase inhibitors against Alzheimer’s disease
1个月前
已完结
Design, Synthesis, Molecular Dynamics Simulations, and Biological Evaluation of PB2 Inhibitors as Anti-Influenza A Virus Agent
1个月前
已完结
Mining the CRBN target space redefines rules for molecular glue–induced neosubstrate recognition
1个月前
已完结
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