Lv2
136 积分 2025-09-21 加入
Targeting σ2R/TMEM97 with novel aminotetralins
1个月前
已完结
Promising anticonvulsant and/or analgesic compounds among 5-chloro-2- or 5-chloro-4-methyl derivatives of xanthone coupled to aminoalkanol moieties—Design, synthesis and pharmacological evaluation
1个月前
已完结
Discovery of WLB-89462, a New Drug-like and Highly Selective σ2 Receptor Ligand with Neuroprotective Properties
1个月前
已完结
The molecular mechanism of the effects of the anti-neuropathic ligands on the modulation of the Sigma-2 receptor: An in-silico study
1个月前
已完结
AlphaFold2 structures guide prospective ligand discovery
1个月前
已完结
First-In-Class Thiosemicarbazone Metal Complexes Targeting the Sigma-2 Receptor (S2R) as an Innovative Strategy against Pancreatic Cancer
1个月前
已完结
One-pot synthesis of trifluoromethyl amines and perfluoroalkyl amines with CF3SO2Na and RfSO2Na
2个月前
已完结
Synthesis and Structure–Activity Relationship Studies of Conformationally Flexible Tetrahydroisoquinolinyl Triazole Carboxamide and Triazole Substituted Benzamide Analogues as σ2 Receptor Ligands
2个月前
已完结
Computational screening of natural and natural-like compounds to identify novel ligands for sigma-2 receptor
2个月前
已完结
Synthesis, binding, and functional properties of tetrahydroisoquinolino-2-alkyl phenones as selective σ2R/TMEM97 ligand
2个月前
已完结
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