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1344 积分 2026-04-24 加入
Practical Crystallization Strategies for Medicinal Chemists
1小时前
已完结
Discovery of a Novel Potent and Orally Efficacious PGK1 Inhibitor C67–47 for the Treatment of Human Pancreatic Cancer
21天前
已完结
Leveraging Structure-Based Design to Overcome Class III RTK Off-Target Activity in the Development of Selective Wild-Type KIT Inhibitors
27天前
已完结
Syntheses of Substituted α,β-Unsaturated δ-Lactams from N-Boc-2,4-dioxopiperidine
1个月前
已完结
GID4-Recruiting PROTACs for BRD4 Degradation Overcome Resistance Driven by CRBN and VHL Deficiency
1个月前
已完结
A bivalent molecular glue linking lysine acetyltransferases to oncogene-induced cell death
1个月前
已完结
AI-driven PROTAC design overcomes oncogenic resilience by eliminating the CLIP1-LTK fusion protein
1个月前
已完结
Proteolysis-Targeting Chimera (PROTAC) Modification of Dovitinib Enhances the Antiproliferative Effect against FLT3-ITD-Positive Acute Myeloid Leukemia Cells
1个月前
已完结
Discovery of a Novel Orally Bioavailable FLT3-PROTAC Degrader for Efficient Treatment of Acute Myeloid Leukemia and Overcoming Resistance of FLT3 Inhibitors
1个月前
已完结
Enhancing Antiproliferative Activity and Selectivity of a FLT-3 Inhibitor by Proteolysis Targeting Chimera Conversion
1个月前
已完结
Enhanced dielectric, ferroelectric, and low-frequency energy harvesting performance in PVDF-(Ba,Ca)(Sn,Ti)O3 composites: Multiscale structure-property insights
51分钟前
已采纳
A structural topology design method based on principal stress line
20天前
已采纳
Accurate Multi-View Stereo 3D Reconstruction for Cost-Effective Plant Phenotyping
20天前
已采纳
A stem and progenitor cell–derived gene expression signature is prognostic for survival in myelofibrosis
20天前
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CSF-1R inhibition and lenalidomide synergize to promote myeloma control after autologous stem cell transplantation
20天前
已采纳
Maintaining low friction coefficient and ultralow wear in metal-filled PTFE composites
20天前
已采纳
Ultra-low-crosstalk silicon switches driven thermally and electrically
21天前
已采纳
Computational characterization of the temperature field in coaxial nitrogen injection under supercritical conditions
21天前
已采纳
Microbial communication in saline environments: quorum sensing and the future of anaerobic wastewater treatment
21天前
已采纳
Inducible Degradation of the Human SMC5/6 Complex Reveals an Essential Role Only during Interphase
21天前
已采纳
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