Lv3
336 积分 2026-04-24 加入
A bivalent molecular glue linking lysine acetyltransferases to oncogene-induced cell death
6天前
已完结
AI-driven PROTAC design overcomes oncogenic resilience by eliminating the CLIP1-LTK fusion protein
6天前
已完结
Proteolysis-Targeting Chimera (PROTAC) Modification of Dovitinib Enhances the Antiproliferative Effect against FLT3-ITD-Positive Acute Myeloid Leukemia Cells
8天前
已完结
Discovery of a Novel Orally Bioavailable FLT3-PROTAC Degrader for Efficient Treatment of Acute Myeloid Leukemia and Overcoming Resistance of FLT3 Inhibitors
8天前
已完结
Enhancing Antiproliferative Activity and Selectivity of a FLT-3 Inhibitor by Proteolysis Targeting Chimera Conversion
8天前
已完结
Discovery of Potent Dual PROTAC Degraders Targeting BET-Kinase To Overcome FLT3 Inhibitor Resistance
8天前
已完结
Infigratinib Phosphate
8天前
已完结
Discovery of a Potent, Selective and In Vivo Active Aurora A PROTAC Degrader from a Promiscuous Kinase Inhibitor
28天前
已完结
Ubiquitin-specific proximity labeling for the identification of E3 ligase substrates
1个月前
已完结
Discovery of TYRA-300: First Oral Selective FGFR3 Inhibitor for the Treatment of Urothelial Cancers and Achondroplasia
1个月前
已完结
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