Lv1
42 积分 2023-11-15 加入
Facile Construction of N ‐Methylated Tertiary Amines via Catalyst‐Free Consecutive Reductive Amination/ N ‐Methylation of Carbonyl Compounds With Amines Using DMSO and HCO 2 H/NEt 3
13天前
已完结
Structure–activity relationship study of central pyridine-derived TYK2 JH2 inhibitors: Optimization of the PK profile through C4′ and C6 variations
16天前
已完结
Allosteric inhibition of JAK2 with lysine-reactive compounds that bind the pseudokinase domain
16天前
已完结
Harnessing tyrosine kinase 2: Breakthroughs in autoimmune disease and cancer therapy
1个月前
已完结
Allosteric inhibition of JAK2 with lysine-reactive compounds that bind the pseudokinase domain
1个月前
已完结
Insights on JAK2 Modulation by Potent, Selective, and Cell-Permeable Pseudokinase-Domain Ligands
1个月前
已完结
Structure–activity relationship study of central pyridine-derived TYK2 JH2 inhibitors: Optimization of the PK profile through C4′ and C6 variations
1个月前
已完结
Identification of a novel benzyloxy-terminated scaffold as a potent and selective TYK2 inhibitor for anti-inflammatory therapy
1个月前
已完结
Pharmacokinetics and Metabolism of ARV‐393, a BCL6 PROTAC Degrader, in Dogs by UPLC–MS/MS and UPLC‐Q‐Exactive Orbitrap‐HRMS
1个月前
已完结
NX-5948: a Bruton’s tyrosine kinase degrader in Ph. Ia/Ib for patients with advanced B-cell malignancies
1个月前
已完结
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