Lv7
4800 积分 2024-07-26 加入
Bicyclo[1.1.1]pentane as a Phenyl Isosteric Replacement
4天前
已完结
Cyclic Peptide PROTACs Restore VHL-Mediated HIF-1α Degradation in Hypoxia
27天前
已完结
Discovery and Preclinical Pharmacology of NX-2127, an Orally Bioavailable Degrader of Bruton’s Tyrosine Kinase with Immunomodulatory Activity for the Treatment of Patients with B Cell Malignancies
29天前
已完结
Kinetics-Driven Drug Design Strategy for Next-Generation Acetylcholinesterase Inhibitors to Clinical Candidate
29天前
已完结
From discovery to clinic: Medicinal chemistry strategies for PROTAC linker optimization
29天前
已完结
Targeted protein degradation: elements of PROTAC design
1个月前
已完结
Rationalizing PROTAC-Mediated Ternary Complex Formation Using Rosetta
1个月前
已完结
Discovery of Highly Potent and Selective, Orally Bioavailable BTK-Targeting PROTACs Featuring Novel CRBN-Binding Warheads
1个月前
已完结
Design and Synthesis of Novel Cereblon Binders for Use in Targeted Protein Degradation
1个月前
已完结
Degrader–Antibody Conjugates: Emerging New Modality
1个月前
已完结
皖公网安备34019202002308
