Lv14
80 积分 2024-08-08 加入
The role of hydrophilic linkers in next-generation antibody-drug conjugates
3天前
已完结
Comprehensive preclinical pharmacokinetic evaluations of trastuzumab deruxtecan (DS-8201a), a HER2-targeting antibody-drug conjugate, in cynomolgus monkeys
7天前
已完结
Antibody-Drug Conjugates Against Multidrug-Resistant Cancers: Biomarker-Guided Patient Selection, Payload Engineering, Linker Chemistry, and Bystander Effects
8天前
已完结
Design and synthesis of novel allosteric MEK inhibitor CH4987655 as an orally available anticancer agent
9天前
已完结
Structure based design of novel 6,5 heterobicyclic mitogen-activated protein kinase kinase (MEK) inhibitors leading to the discovery of imidazo[1,5-a] pyrazine G-479
10天前
已关闭
Design, Synthesis, and Biological Evaluation of MEK PROTACs
10天前
已完结
Testing of the Topoisomerase 1 Inhibitor Genz644282 by the Pediatric Preclinical Testing Program
17天前
已完结
14-Aminocamptothecins: their synthesis, preclinical activity, and potential use for cancer treatment
17天前
已完结
Antitumor activities and pharmacokinetics of silatecans DB-67 and DB-91
17天前
已完结
Safety, Tolerability, and Pharmacokinetics of a Capsule Formulation of DRF‐1042, a Novel Camptothecin Analog, in Refractory Cancer Patients in a Bridging Phase I Study
17天前
已完结