Lv4
640 积分 2025-10-31 加入
Artemisinin-derived hydrophobic tags: structural modification and structure-activity relationship exploration of HDAC6/1 targeting degraders with potent antileukemic efficacy
4天前
已完结
Targeted Cholinesterase Inhibition by Novel Oxoisoindoline Derivatives with Potential Activity Against BACE1 and Serotonin Receptor
16天前
已完结
Artemisinin-derived hydrophobic tags: structural modification and structure-activity relationship exploration of HDAC6/1 targeting degraders with potent antileukemic efficacy
17天前
已完结
Discovery of molecular glue degrader for treatment of IMiDs-resistant multiple myeloma based on GLUT-mediated tumor targeting strategy
18天前
已完结
Design, synthesis, and biological evaluation of selective HDAC6 inhibitors featuring an N-benzyl-2-(aryl/heteroaryl)acetamide cap
18天前
已完结
Novel 2-amino-4-(1H-imidazol)pyridine derivatives as potent brain-penetrant EGFR mutant inhibitors: Design, synthesis, biological evaluation, and molecular modeling study
18天前
已完结
Design, synthesis, and biological evaluation of novel probe-quality EGFR degraders targeting wild-type and Del19 mutation
18天前
已完结
Alpha-Particle Therapy with an Actinium-225 Labeled Bivalent Inhibitor of Prostate-Specific Membrane Antigen is Therapeutically Efficacious in a Mouse Model of Prostate Cancer
19天前
已完结
Fragment-based structure-activity relationship analysis of CK-571 reveals non-interacting groups drive smooth muscle myosin selectivity
19天前
已完结
Conformationally Tuned Cyclic RGD Peptides for Integrin-Subtype-Selective PET/CT Imaging
19天前
已完结
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