Lv31
368 积分 2023-01-28 加入
The MEK–RAF molecular glue IK-595 has potent antitumor activity across RAS/MAPK pathway-altered cancers
2个月前
已完结
The MEK–RAF molecular glue IK-595 has potent antitumor activity across RAS/MAPK pathway-altered cancers
2个月前
已完结
Architecture of autoinhibited and active BRAF–MEK1–14-3-3 complexes
2个月前
已完结
Covalent inhibitors of the PI3Kα RAS binding domain impair tumor growth driven by RAS and HER2
3个月前
已完结
BBO-10203 inhibits tumor growth without inducing hyperglycemia by blocking RAS-PI3Kα interaction
3个月前
已完结
Lysosomal LAMP proteins regulate lysosomal pH by direct inhibition of the TMEM175 channel
5个月前
已完结
Discovery of Selective Inhibitors for the Lysosomal Parkinson’s Disease Channel TMEM175
5个月前
已完结
Structural insights into the activation of TMEM175 by small molecule
5个月前
已完结
Structural basis for NaV1.7 inhibition by pore blockers
8个月前
已完结
Characterization of the molecular interactions of interleukin-8 (CXCL8), growth related oncogen α (CXCL1) and a non-peptide antagonist (SB 225002) with the human CXCR2
9个月前
已完结
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