Lv4
436 积分 2023-01-28 加入
Molecular Determinants of Response and Rational Drug Combinations for Antibody-Drug Conjugates (ADCs) with Topoisomerase I (TOP1) Inhibitor Payloads
25天前
已完结
Structure–activity relationship (SAR) studies on substituted N-(pyridin-3-yl)-2-amino-isonicotinamides as highly potent and selective glycogen synthase kinase-3 (GSK-3) inhibitors
1个月前
已完结
The MEK–RAF molecular glue IK-595 has potent antitumor activity across RAS/MAPK pathway-altered cancers
4个月前
已完结
The MEK–RAF molecular glue IK-595 has potent antitumor activity across RAS/MAPK pathway-altered cancers
4个月前
已完结
Architecture of autoinhibited and active BRAF–MEK1–14-3-3 complexes
4个月前
已完结
Covalent inhibitors of the PI3Kα RAS binding domain impair tumor growth driven by RAS and HER2
4个月前
已完结
BBO-10203 inhibits tumor growth without inducing hyperglycemia by blocking RAS-PI3Kα interaction
4个月前
已完结
Lysosomal LAMP proteins regulate lysosomal pH by direct inhibition of the TMEM175 channel
7个月前
已完结
Discovery of Selective Inhibitors for the Lysosomal Parkinson’s Disease Channel TMEM175
7个月前
已完结
Structural insights into the activation of TMEM175 by small molecule
7个月前
已完结
皖公网安备34019202002308
