Lv6
1670 积分 2023-07-16 加入
A Traceless Directing Group for C–H Borylation
4天前
已完结
One-Pot Homologation of Boronic Acids: A Platform for Diversity-Oriented Synthesis
12天前
已完结
A Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth and Induces Antitumor Immunity in Gastrointestinal Cancer
2个月前
已完结
Abstract B014: A mechanistically distinct pan-RAS inhibitor, ADT-007, with robust antitumor activity evades resistance common to mutant-specific and pan-RAS Inhibitors
2个月前
已完结
The discovery and preclinical characterization of 6-chloro-N-(2-(4,4-difluoropiperidin-1-yl)-2-(2-(trifluoromethyl)pyrimidin-5-yl)ethyl)quinoline-5-carboxamide based P2X7 antagonists
2个月前
已完结
Identification of false positives in “HTS hits to lead”: The application of Bayesian models in HTS triage to rapidly deliver a series of selective TRPV4 antagonists
4个月前
已完结
Discovery of Novel Snail Inhibitors Derived from Omeprazole for Antiatherosclerotic Therapy: A Structure-Based Approach
4个月前
已完结
Discovery and Optimization of 4-Aminopteridin-7(8 H )-one Derivatives as Potent and Selective mTOR Inhibitors with Favorable Pharmacodynamic and Safety Characteristics
4个月前
已完结
Rational Design of Novel pyrazolo[4,3c]quinoline Derivatives as Potent, Selective, and Orally Bioavailable ATM Inhibitors with Promising In Vivo Efficacy
4个月前
已完结
A Pragmatic PBPK-Driven Strategy to Guide ADME Characterization and Early Human PK Prediction for ECCS Class 1B/3B Compounds
4个月前
已完结
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