Lv41
500 积分 2026-01-07 加入
Polygonatum sibiricum polysaccharide delays age-related decline and preserves muscle integrity in Caenorhabditis elegans by modulating the daf-2/IIS pathway
1小时前
待确认
ATF4 in cellular stress, ferroptosis, and cancer
1个月前
已完结
NXP800 activates the unfolded protein response, altering AR and E2F function to impact castration-resistant prostate cancer growth
1个月前
已完结
Activating GCN2 and subsequently the Unfolded Protein Response with the small oral molecule NXP800 delays tumor growth in osteosarcoma
1个月前
已完结
Discovery of HC-7366: An Orally Bioavailable and Efficacious GCN2 Kinase Activator
1个月前
已完结
Protein quality control through endoplasmic reticulum-associated degradation maintains haematopoietic stem cell identity and niche interactions
1个月前
已完结
Discovery of DNL343: A Potent, Selective, and Brain-Penetrant eIF2B Activator Designed for the Treatment of Neurodegenerative Diseases
3个月前
已完结
Neurotranscriptomic and behavioral effects of ISRIB, and its therapeutic effects in the traumatic brain injury model in zebrafish
3个月前
已完结
Harnessing viral strategies to reverse cognitive dysfunction through the integrated stress response
3个月前
已完结
Stability and Degradation-based Proteome Profiling Reveals Cannabidiol as a Promising CDC123-eIF2γ Inhibitor for Colorectal Cancer Therapy
3个月前
已完结
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