Lv4
500 积分 2026-01-07 加入
NXP800 activates the unfolded protein response, altering AR and E2F function to impact castration-resistant prostate cancer growth
3小时前
待确认
Activating GCN2 and subsequently the Unfolded Protein Response with the small oral molecule NXP800 delays tumor growth in osteosarcoma
3小时前
待确认
Discovery of HC-7366: An Orally Bioavailable and Efficacious GCN2 Kinase Activator
4小时前
待确认
Protein quality control through endoplasmic reticulum-associated degradation maintains haematopoietic stem cell identity and niche interactions
4小时前
待确认
Discovery of DNL343: A Potent, Selective, and Brain-Penetrant eIF2B Activator Designed for the Treatment of Neurodegenerative Diseases
1个月前
已完结
Neurotranscriptomic and behavioral effects of ISRIB, and its therapeutic effects in the traumatic brain injury model in zebrafish
1个月前
已完结
Harnessing viral strategies to reverse cognitive dysfunction through the integrated stress response
1个月前
已完结
Stability and Degradation-based Proteome Profiling Reveals Cannabidiol as a Promising CDC123-eIF2γ Inhibitor for Colorectal Cancer Therapy
1个月前
已完结
The Integrated Stress Response in Cancer: Paradox and Therapeutic Promise
4个月前
已完结
Discovery of DNL343: A Potent, Selective, and Brain-Penetrant eIF2B Activator Designed for the Treatment of Neurodegenerative Diseases
4个月前
已完结
皖公网安备34019202002308
