Lv41
522 积分 2024-10-29 加入
Rationally designed Pyrazolo[1,5-a]pyrimidines as dual inhibitors of CA IX/XII and CDK6: A novel approach for NSCLC treatment
20天前
已完结
Selective CDK6 Degradation via the KLHDC2 E3 Ubiquitin Ligase
20天前
已完结
Discover of a highly effective covalent inhibitor of CDK6 for triple-negative breast cancer treatment
20天前
已完结
A PROTAC-inspired bifunctional small molecule recruits CDK6 to target EYA2 degradation and suppress breast tumor growth
20天前
已完结
Design, synthesis, and biological activities of novel camphoric acid derivatives bearing α -aminophosphonate moiety
1个月前
已完结
Hedyotis diffusa injection modulates the ferroptosis in bladder cancer via CAV1/JUN/VEGFA
1个月前
已完结
4-Arylindolines Bearing a Pyrido[3,2-d]pyrimidine Scaffold as Dual Inhibitors of the PD-1/PD-L1 Interaction and NAMPT for Targeting Tumor Immunoevasion and Metabolism
1个月前
已完结
DCPDC-Mediated Facile Amide-Bond Formation of Non-Nucleophilic and Hindered Amines
2个月前
已完结
Cyclin dependent kinase (CDK) inhibitors as anticancer drugs
4个月前
已完结
The expanding repertoire of covalent warheads for drug discovery
4个月前
已完结