Lv7
4770 积分 2023-02-17 加入
Detection of antibody-conjugate payload in cynomolgus monkey serum by a high throughput capture LC–MS/MS bioanalysis method
5小时前
已完结
Release of Anticancer Agents in the Tumor Microenvironment Using Cathepsin B and Cathepsin L Cleavable Drug-Linker Constructs
24天前
已关闭
Intracellular protein editing enables incorporation of noncanonical residues in endogenous proteins
1个月前
已完结
Physiologically Based Pharmacokinetic Modeling as a Tool to Predict Drug Interactions for Antibody-Drug Conjugates
1个月前
已完结
Angiotensin II increases expression and secretion of cathepsin F in cultured human monocyte-derived macrophages: An angiotensin II type 2 receptor-mediated effect
2个月前
已完结
Discovery and Safety Profiling of a Potent Preclinical Candidate, (4-[4-[[(3R)-3-(Hydroxycarbamoyl)-8-azaspiro[4.5]decan-3-yl]sulfonyl]phenoxy]-N-methylbenzamide) (CM-352), for the Prevention and Treatment of Hemorrhage
2个月前
已完结
An in Vitro Assay Using Cultured Kupffer Cells Can Predict the Impact of Drug Conjugation on in Vivo Antibody Pharmacokinetics
3个月前
已完结
Beyond Cytotoxic Potency: Disposition Features Required to Design ADC Payload
3个月前
已完结
ADME and DMPK considerations for the discovery and development of antibody drug conjugates (ADCs)
3个月前
已完结
Mechanisms of ADC Toxicity and Strategies to Increase ADC Tolerability
3个月前
已完结
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