Lv1
40 积分 2025-10-13 加入
Discovery of a 3-(4-Pyrimidinyl) Indazole (MLi-2), an Orally Available and Selective Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitor that Reduces Brain Kinase Activity
7天前
已完结
Restoration of striatal neuroprotective pathways by kinase inhibitor treatment of Parkinson’s disease–linked LRRK2 -mutant mice
8天前
已完结
LRRK2 regulates production of reactive oxygen species in cell and animal models of Parkinson’s disease
8天前
已完结
MLi-2, a Potent, Selective, and Centrally Active Compound for Exploring the Therapeutic Potential and Safety of LRRK2 Kinase Inhibition
8天前
已完结
Macrophage LRRK2 hyperactivity impairs autophagy and induces Paneth cell dysfunction
1个月前
已完结
Reduction of Z alpha-1 antitrypsin polymers in human iPSC-hepatocytes and mice by LRRK2 inhibitors
5个月前
已完结
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